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249,251 Dyslipidemia also affects Schwann cells, leading to mitochondrial dysfunction, endoplasmic reticulum stress, and oxidative stress, ultimately causing cell death

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Camras C.B., Bito L.Z., Toris C.B

Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling

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The constitutive activation has been documented in various cancers, including hepatocellular carcinoma, where it promotes chemoresistance, metabolic reprogramming favoring tumor growth, and evasion of apoptosis (78, 79)